ncRNA basic information
ncRNA ID:
MI0000300
ncRNA Database:
miRBase
ncRNA Name:
miR-223
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
STAT5A
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
The expression levels of miRNA were determined by qRT-PCR and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs. Cell migration was detected by transwell migration and invasion assay.
Drug Response:
sensitive
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
cell line (HEK293, MDAMB231, MCF7, HeLa )
Other information
Title:
miR-223 is a coordinator of breast cancer progression as revealed by bioinformatics predictions.
Journal:
PLoS One
Published:
2014
PubMed ID:
24400121