ncRNA basic information
ncRNA ID:
MI0000285
ncRNA Database:
miRBase
ncRNA Name:
miR-205
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
Real-time RT-PCR
ncRNA Target Gene:
RAB27A and LAMP3
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The role of miR-205 in prostate cancer cells was detected using Caspase-3 catalytic activity assay, Real-time RT-PCR, immunoblotting analysis, fluorescence microscopy analyses, gene expression analysis, etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
prostate cancer
Tissue/Cell:
cell line ( DU145, PC-3 )
Other information
Title:
miR-205 impairs the autophagic flux and enhances cisplatin cytotoxicity in castration-resistant prostate cancer cells.
Journal:
Biochem Pharmacol
Published:
2014
PubMed ID:
24370341