ncRNA basic information
ncRNA ID:
MI0000454
ncRNA Database:
miRBase
ncRNA Name:
miR-137
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
CAR
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
The role of miR-137 in neuroblastoma cells was detected using quantitative real-time PCR, molecular cloning and assays, chromatin immunoprecipitation assay, cellular assays, soft agar colony-formation assay, mouse xenografts and immunohistochemical analyses, etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
neuroblastoma
Tissue/Cell:
cell line (293T, HepG2, LS174,UKF-NB3, UKF-NB3/Dox-R,)
Other information
Title:
miR-137 regulates the constitutive androstane receptor and modulates doxorubicin sensitivity in parental and doxorubicin-resistant neuroblastoma cells.
Journal:
Oncogene
Published:
2014
PubMed ID:
23934188