ncRNA basic information
ncRNA ID:
MI0000087
ncRNA Database:
miRBase
ncRNA Name:
miR-29
ncRNA Type:
miRNA
ncRNA Expression:
down-regulated
ncRNA Method:
RT-qPCR
ncRNA Target Gene:
COL1A1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined by reverse transcription and quantitative polymerase chain reaction and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs. Flow Cytometric Assay was used to determine if cells were viable, apoptotic, or necrotic.
Drug Response:
resistant
Cancer basic information
Cancer:
ovarian cancer
Tissue/Cell:
cell line ( CP70, A2780, HeyC2, SKOV3,CP70sps)
Other information
Title:
Downregulation of miR-29 contributes to cisplatin resistance of ovarian cancer cells.
Journal:
Int J Cancer
Published:
2014
PubMed ID:
23904094