ncRNA basic information
ncRNA ID:
MI0000804
ncRNA Database:
miRBase
ncRNA Name:
miR-328
ncRNA Type:
miRNA
ncRNA Expression:
down-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
ABCG2
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB01204 (APRD00371)
Drug Name:
Mitoxantrone
Drug Method:
The expression levels of miRNA were determined by Quantitative Real-Time Reverse Transcription-PCR. Luciferase activity assay was used to verify the target genes of miRNAs.
Drug Response:
resistant
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
cell line (MCF-7,MCF-7/MX100)
Other information
Title:
MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells.
Journal:
Mol Pharmacol
Published:
2009
PubMed ID:
19270061