ncRNA basic information
ncRNA ID:
MI0000109
ncRNA Database:
miRBase
ncRNA Name:
miR-103
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
Real-time RT-PCR
ncRNA Target Gene:
RAD51 and RAD51D
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined by Real-time RT-PCR and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs.Cell survival was assessed by crystal violet staining as described .
Drug Response:
sensitive
Cancer basic information
Cancer:
cancer
Tissue/Cell:
cell line (U2OS, HeLa, H1299)
Other information
Title:
Systematic screen identifies miRNAs that target RAD51 and RAD51D to enhance chemosensitivity.
Journal:
Mol Cancer Res
Published:
2013
PubMed ID:
24088786