ncRNA basic information
ncRNA ID:
MI0000077
ncRNA Database:
miRBase
ncRNA Name:
miR-21
ncRNA Type:
miRNA
ncRNA Expression:
down-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
Bcl-2
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
The role of miR-21 in leukemia cells was detected using protein expression and immunoprecipitation analysis, microRNA expression analysis, BrdU Proliferation Assay, cell cycle analysis , etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
leukemia
Tissue/Cell:
cell line (K562,KYO-1)
Other information
Title:
Targeting miR-21 induces autophagy and chemosensitivity of leukemia cells.
Journal:
Curr Drug Targets
Published:
2013
PubMed ID:
23834154