ncRNA basic information
ncRNA ID:
MIMAT0000753
ncRNA Database:
miRBase
ncRNA Name:
miR-342-3p
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
predicted
drug basic information
Drug ID:
DB01177 (APRD00126)
Drug Name:
Idarubicine
Drug Method:
We applied an miRNA microarray followed by PCR verification of 33 available diagnostic bone marrow core biopsies from 33 acute myeloid leukemia patients including 15 chemoresistant and 18 chemosensitive patients. Further validation of miR-532-5p and miR-363 expression by quantitative RT-PCR confirmed microarray analysis results. Genes targeted by miR-363 include RGS17 and HIPK3, both reported to be associated with drug response.
Drug Response:
resistant
Cancer basic information
Cancer:
acute myeloid leukemia
Tissue/Cell:
tissue and cell line
Other information
Title:
MicroRNA profiling in chemoresistant and chemosensitive acute myeloid leukemia.
Journal:
Cytogenet Genome Res
Published:
2013
PubMed ID:
23689423