ncRNA basic information
ncRNA ID:
MI0000738
ncRNA Database:
miRBase
ncRNA Name:
miR-302a
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined by real-time quantitative PCR and those of protein were by Western blot analysis. The CCK-8 assay was used to monitor the growth of the cells.Flow cytometric analysis was used to determine if cells were viable, apoptotic, or necrotic.
Drug Response:
sensitive
Cancer basic information
Cancer:
testicular embryonal carcinoma
Tissue/Cell:
cell line (NT2, NCCIT)
Other information
Title:
MicroRNA-302a sensitizes testicular embryonal carcinoma cells to cisplatin-induced cell death.
Journal:
J Cell Physiol
Published:
2013
PubMed ID:
23625774