ncRNA basic information
ncRNA ID:
MI0000283
ncRNA Database:
miRBase
ncRNA Name:
miR-203
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
Real-time RT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00619 (APRD01028, EXPT02967, DB03261)
Drug Name:
Imatinib
Drug Method:
The expression levels of miRNA were determined by Real-time RT-PCR and those of protein were by Western blot analysis. MTT assay was used to test the drug-resistant phenotype changes in cancer cells via overregulation of miRNAs.
Drug Response:
sensitive
Cancer basic information
Cancer:
chronic myeloid leukemia
Tissue/Cell:
cell line (BaF3,BaF3-BCR/ABLT315I)
Other information
Title:
Inhibition of BCR/ABL protein expression by miR-203 sensitizes for imatinib mesylate.
Journal:
PLoS One
Published:
2013
PubMed ID:
23613955