ncRNA basic information
ncRNA ID:
MI0000074/MI0000075
ncRNA Database:
miRBase
ncRNA Name:
miR-19b
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
PTEN
ncRNA Pathway:
PTEN-AKT pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The role of miR-19a/b in human gastric cancer cells was detected using quantitative RT-PCR, oligonucleotide transfection,cell apoptosis assays,fluorescence intensity assay of intracellular ADR, western blot analysis, etc.
Drug Response:
resistant
Cancer basic information
Cancer:
stomach cancer
Tissue/Cell:
cell line ( SGC7901,SGC7901/VCR, SGC7901/ADR)
Other information
Title:
MicroRNA-19a/b regulates multidrug resistance in human gastric cancer cells by targeting PTEN.
Journal:
Biochem Biophys Res Commun
Published:
2013
PubMed ID:
23603256