ncRNA basic information
ncRNA ID:
MI0000477
ncRNA Database:
miRBase
ncRNA Name:
miR-146a
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qPCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
First,we analyzed the miRNA expression profiles of primary EOC tumors and their respective omental metastases from 9 patients using miRNA Taqman qPCR arrays. Then,the role of miR in ovarian cancer cells was detected using, laser capture microdissection and miRNA measurement, cell viability, survival and spheroid assays, affymetrix microarrays, miRNA ISH,etc.
Drug Response:
resistant
Cancer basic information
Cancer:
ovarian cancer
Tissue/Cell:
tissue and cell line (OVCAR-8, SKOV-3,IGROV-1)
Other information
Title:
Identification of ovarian cancer metastatic miRNAs.
Journal:
PLoS One
Published:
2013
PubMed ID:
23554878