ncRNA basic information
ncRNA ID:
NA
ncRNA Database:
circBase
ncRNA Name:
circBA9.3
ncRNA Type:
circRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00619 (APRD01028, EXPT02967, DB03261)
Drug Name:
Imatinib
Drug Method:
The role of CircBA9.3 in leukaemic cancer was detected using Third-generation digital PCR system (3D-dPCR), quantitative real-time PCR, proliferation and drug resistance assays, flow cytometry analyses and western blots, etc.
Drug Response:
resistant
Cancer basic information
Cancer:
chronic myeloid leukemia
Tissue/Cell:
cell line ( K562 and Ku812)
Other information
Title:
CircBA9.3 supports the survival of leukaemic cells by up-regulating c-ABL1 or BCR-ABL1 protein levels.
Journal:
Blood Cells Mol Dis
Published:
2018
PubMed ID:
30224298