ncRNA basic information
ncRNA ID:
MI0000736/MI0000254
ncRNA Database:
miRBase
ncRNA Name:
miR-30c
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
TWF1 and IL-11
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
The role of miR-30c in human breast tumour cells was detected usingreal-time PCR, cell growth assays, Western blot, luciferase assay,Immunofluorescence, histology, and microscope,Tumour transplantation and chemotherapy in mice,etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
breast tumor
Tissue/Cell:
tissue and cell line (T47D, MCF-7, MDA-MB-231, BT-20, HCC-70, HCC-38)
Other information
Title:
MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11.
Journal:
Nat Commun
Published:
2013
PubMed ID:
23340433