ncRNA basic information
ncRNA ID:
MI0000290
ncRNA Database:
miRBase
ncRNA Name:
miR-214
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
Bcl2l2
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined by qRT-PCR and those of protein were by Western blot analysis. TUNEL staining was used to detect apoptotic cell death.Based on bioinformatic prediction target .
Drug Response:
sensitive
Cancer basic information
Cancer:
cervical cancer
Tissue/Cell:
tissue and cell line (HeLa,C-33A,HeLa/miR-214, HeLa/Neg-Ctrl)
Other information
Title:
MiR-214 reduces cell survival and enhances cisplatin-induced cytotoxicity via down-regulation of Bcl2l2 in cervical cancer cells.
Journal:
FEBS Lett
Published:
2013
PubMed ID:
23337879