ncRNA basic information
ncRNA ID:
NA
ncRNA Database:
circBase
ncRNA Name:
chr12:179378341 179392104
ncRNA Type:
circRNA
ncRNA Expression:
down-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
predicted
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
CircRNA expression profile was performed in three paired human chemoresistant and chemosensitive OS cell lines by next-generation sequencing. Quantitative real-time-PCR (qRT-PCR) was used to confirm next-generation sequencing data. Bioinformatics analysis was conducted to predict their functions.
Drug Response:
resistant
Cancer basic information
Cancer:
osteosarcoma
Tissue/Cell:
tissue and cell line (MG63,MG63/DXR,U2OS,U2OS/DXR,KHOS and KHOS/DXR)
Other information
Title:
Screening circular RNA related to chemotherapeutic resistance in osteosarcoma by RNA sequencing.
Journal:
Epigenomics
Published:
2018
PubMed ID:
30191736