ncRNA basic information
ncRNA ID:
hsa-circRNA-007874
ncRNA Database:
circBase
ncRNA Name:
circRNA-MTO1
ncRNA Type:
circRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-qPCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB04331 (EXPT02296)
Drug Name:
Monastrol
Drug Method:
The role of Circular RNA-MTO1 in breast cancer cells was detected using CCK-8 assay, RT-qPCR, RNA pulldown and mass spectrometry, Fluorescence in situ hybridization analysis (FISH),Immunohistochemistry (IHC), western blotting and cell invasion assay, etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
cell line (MDA-MB-231, MCF-7, MDA-MB-453, SKBR-3, T47D, MDA-MB-468,MCF-7-R and MDA-MB-231R)
Other information
Title:
Circular RNA-MTO1 suppresses breast cancer cell viability and reverses monastrol resistance through regulating the TRAF4/Eg5 axis.
Journal:
Int J Oncol
Published:
2018
PubMed ID:
30015883