ncRNA basic information
ncRNA ID:
hsa_circ_0001821
ncRNA Database:
circBase
ncRNA Name:
circPVT1
ncRNA Type:
circRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
ABCB1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
The role of circPVT1 in osteosarcoma cells was detected using qRT-PCR, CCK8 assay, colony formation assay and western blot analysis, etc.
Drug Response:
resistant
Cancer basic information
Cancer:
osteosarcoma
Tissue/Cell:
cell line (SaoS2, KHOS, U2OS, MG63,U2OSR,KHOSR)
Other information
Title:
Overexpressed circPVT1, a potential new circular RNA biomarker, contributes to doxorubicin and cisplatin resistance of osteosarcoma cells by regulating ABCB1.
Journal:
Int J Biol Sci
Published:
2018
PubMed ID:
29559849