ncRNA basic information
ncRNA ID:
MI0000443/MI0000444/MI0000445
ncRNA Database:
miRBase
ncRNA Name:
miR-124
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
AURKA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00853 (APRD00557)
Drug Name:
Temozolomide
Drug Method:
The role of miR-124 in glioblastoma cells was detected using quantitative real-time PCR, western blot and immunohistochemistry (IHC), cell proliferation assay, In vivo studies and dual luciferase assay, etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
glioblastoma
Tissue/Cell:
tissue and cell line (U-118 MG, LN229, T98G, U138MG, U-87 MG, M059K, M059J,A-172)
Other information
Title:
miR-124 suppresses glioblastoma growth and potentiates chemosensitivity by inhibiting AURKA.
Journal:
Biochem Biophys Res Commun
Published:
2017
PubMed ID:
28242198