ncRNA basic information
ncRNA ID:
MIMAT0004679
ncRNA Database:
miRBase
ncRNA Name:
miR-296-3p
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
EAG1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00853 (APRD00557)
Drug Name:
Temozolomide
Drug Method:
The expression levels of miRNA were determined by qRT-PCR and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs. The CCK-8 assay was used to monitor the growth of the cells .Cell migration was detected by invasion assay.
Drug Response:
sensitive
Cancer basic information
Cancer:
glioblastoma
Tissue/Cell:
cell line (U251,U251AR)
Other information
Title:
MiR-296-3p regulates cell growth and multi-drug resistance of human glioblastoma by targeting ether-a-go-go (EAG1).
Journal:
Eur J Cancer
Published:
2013
PubMed ID:
22999387