ncRNA basic information
ncRNA ID: MI0000283
ncRNA Database: miRBase
ncRNA Name: miR-203a
ncRNA Type: miRNA
ncRNA Expression: down-regulated
ncRNA Method: RT-PCR,qRT-PCR
ncRNA Target Gene: NA
ncRNA Pathway: NA
Evidence (ncRNA-drug): predicted
drug basic information
Drug ID: DB00515 (APRD00359)
Drug Name: Cisplatin
Drug Method: An in-vitro model of acquired chemotherapy resistance in esophageal adeno- (EAC) and squamous cell carcinoma (ESCC) cells was used, and microRNA expression profiles for cisplatin or 5-fluorouracil (5-FU) resistant variants vs chemotherapy sensitive controls were compared using microarray and quantitative real-time polymerase chain reaction (PCR). The expression of chemotherapy-relevant genes potentially targeted by the dysregulated microRNAs in the chemotherapy resistant variants was also evaluated.
Drug Response: resistant
Cancer basic information
Cancer: esophageal cancer
Tissue/Cell: cell line (OE19,KYSE410)
Other information
Title: MicroRNA signatures in chemotherapy resistant esophageal cancer cell lines.
Journal: World J Gastroenterol
Published: 2014
PubMed ID: 25356050