ncRNA basic information
ncRNA ID:
MI0001729
ncRNA Database:
miRBase
ncRNA Name:
miR-451
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00619 (APRD01028, EXPT02967, DB03261)
Drug Name:
Imatinib
Drug Method:
The role of miR-144/451 in chronic myelogenous leukemia cell K562 was detected usingImmunofluorescence analysis, MTT assay, Real-time quantitative PCR, reporter assay, quantitative chromatin immunoprecipitation,etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
chronic myeloid leukemia
Tissue/Cell:
cell line ( K562, K562R)
Other information
Title:
Myc induced miR-144/451 contributes to the acquired imatinib resistance in chronic myelogenous leukemia cell K562.
Journal:
Biochem Biophys Res Commun
Published:
2012
PubMed ID:
22842456