ncRNA basic information
ncRNA ID:
MIMAT0004777
ncRNA Database:
miRBase
ncRNA Name:
miR-513a-3p
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
Real-time RT-PCR
ncRNA Target Gene:
GSTP1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined by Reverse transcription and real-time PCR analysis (real-time RT-PCR) and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs. The CCK-8 assay was used to monitor the growth of the cells .
Drug Response:
sensitive
Cancer basic information
Cancer:
lung adenocarcinoma
Tissue/Cell:
cell line (A549,A549/CDDP,SPC-A-1)
Other information
Title:
miR-513a-3p sensitizes human lung adenocarcinoma cells to chemotherapy by targeting GSTP1.
Journal:
Lung Cancer
Published:
2012
PubMed ID:
22749944