ncRNA basic information
ncRNA ID:
MI0000289/MI0000269
ncRNA Database:
miRBase
ncRNA Name:
miR-181a
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00987 (APRD00499)
Drug Name:
Ara-C
Drug Method:
miR-181a expression was measured by real-time PCR. Cell viability was detected by MTT assay. Protein expressions were measured by western blotting. Caspase activity was examined by fluorescence assay.
Drug Response:
sensitive
Cancer basic information
Cancer:
leukemia
Tissue/Cell:
cell line (HL-60,HL-60/Ara-C,HEK293T)
Other information
Title:
miR-181a sensitizes resistant leukaemia HL-60/Ara-C cells to Ara-C by inducing apoptosis.
Journal:
J Cancer Res Clin Oncol
Published:
2012
PubMed ID:
22209977