ncRNA basic information
ncRNA ID:
MI0000650
ncRNA Database:
miRBase
ncRNA Name:
miR-200c
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
cyclin D1 and c-myc
ncRNA Pathway:
Beta-catenin signaling pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
he expression of miR-200c in human endometrial tissues was detected by quantitative RT-PCR. The transfection with anti-miRNA (anti-miR) or the premature form of miRNA (pre-miR) was performed to regulate the level of expression of miRNA-200c in endometrial carcinoma cells, HEC-1A and Ishikawa. To identify the target genes for miR-200c, we performed mRNA microarray after pre-miR-200c transfection in HEC-1A cells.
Drug Response:
resistant
Cancer basic information
Cancer:
esophagus adenocarcinoma
Tissue/Cell:
cell line (AN3CA, HEC-1A, Ishikawa, KLE,2774,293)
Other information
Title:
The interactions between MicroRNA-200c and BRD7 in endometrial carcinoma.
Journal:
Gynecol Oncol
Published:
2012
PubMed ID:
22015043