ncRNA basic information
ncRNA ID:
MI0000268
ncRNA Database:
miRBase
ncRNA Name:
miR-34a
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-PCR,qRT-PCR
ncRNA Target Gene:
Cdk6
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The role of miR-34a in bladder cancer cells was detected using RT-PCR, qRT-PCR, transfection,immunoblot analysis, methylation specific PCR, clonogenic assay, senescence assay,flow cytometry, etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
bladder cancer
Tissue/Cell:
cell line(T24,TCCSuP and 5637)
Other information
Title:
MiR-34a chemosensitizes bladder cancer cells to cisplatin treatment regardless of p53-Rb pathway status.
Journal:
Int J Cancer
Published:
2012
PubMed ID:
21702042