ncRNA basic information
ncRNA ID:
MI0000463/MI0000464
ncRNA Database:
miRBase
ncRNA Name:
miR-153
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB01169 (APRD00171)
Drug Name:
Arsenic trioxide
Drug Method:
The expression levels of miRNA were determined by quantitative real-time PCR and those of protein were by Western blot analysis. MTT assay was used to test the drug-resistant phenotype changes in cancer cells via overregulation of miRNAs.
Drug Response:
sensitive
Cancer basic information
Cancer:
leukemia
Tissue/Cell:
cell line ( K562 )
Other information
Title:
miR-153 sensitized the K562 cells to As2O3-induced apoptosis.
Journal:
Med Oncol.
Published:
2012
PubMed ID:
21267675