ncRNA basic information
ncRNA ID:
MI0000283
ncRNA Database:
miRBase
ncRNA Name:
miR-203
ncRNA Type:
miRNA
ncRNA Expression:
down-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
SOCS3
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined by Quantitative real-time reverse transcription PCR and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs.
Drug Response:
sensitive
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
cell line (MCF-7, ZR-75, MDA-MB-231)
Other information
Title:
Anti-miR-203 Upregulates SOCS3 Expression in Breast Cancer Cells and Enhances Cisplatin Chemosensitivity.
Journal:
Genes Cancer
Published:
2011
PubMed ID:
22207897