ncRNA basic information
ncRNA ID:
MIMAT0002828
ncRNA Database:
miRBase
ncRNA Name:
miR-519e*
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
predicted
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
Biopsy samples were collected prior to chemotherapy from 90 gastric cancer patients treated with CF and from 34 healthy volunteers. At the time of disease progression, post-treatment samples were additionally collected from 8 clinical responders. miRNA expression was determined using a custom-designed Agilent microarray. In order to identify a miRNA signature for chemotherapy resistance, we correlated miRNA expression levels with the time to progression (TTP) of disease after CF therapy.
Drug Response:
resistant
Cancer basic information
Cancer:
stomach cancer
Tissue/Cell:
tissue
Other information
Title:
miRNA signature associated with outcome of gastric cancer patients following chemotherapy.
Journal:
BMC Med Genomics
Published:
2011
PubMed ID:
22112324