ncRNA basic information
ncRNA ID:
MI0000090
ncRNA Database:
miRBase
ncRNA Name:
miR-32
ncRNA Type:
miRNA
ncRNA Expression:
down-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00987 (APRD00499)
Drug Name:
Cytarabine
Drug Method:
Public web-based prediction sites under miRbase were used to identify miRNA 32 target binding sites in the 3'UTR of human gene transcripts . The expression levels of miRNA were determined by quantitative RT-PCR and those of protein were by Western blot analysis.
Drug Response:
sensitive
Cancer basic information
Cancer:
myeloid leukemia
Tissue/Cell:
cell line (HL60-G,U937)
Other information
Title:
MicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of AraC-induced apoptosis.
Journal:
Cancer Res
Published:
2011
PubMed ID:
21816906