ncRNA basic information
ncRNA ID: ENSG00000130600
ncRNA Database: Ensembl
ncRNA Name: H19
ncRNA Type: lncRNA
ncRNA Expression: down-regulated
ncRNA Method: qRT-PCR
ncRNA Target Gene: NA
ncRNA Pathway: NA
Evidence (ncRNA-drug): validated
drug basic information
Drug ID: DB00853 (APRD00557)
Drug Name: Temozolomide
Drug Method: The expression levels of lncRNA were determined by qRT-PCR and those of protein were by Western blot analysis. MTT assay was used to test the drug-resistant phenotype changes in cancer cells via overregulation of lncRNAs. Flow Cytometric Assay was used to determine if cells were viable, apoptotic, or necrotic.
Drug Response: sensitive
Cancer basic information
Cancer: glioma
Tissue/Cell: cell line ( U87 and U251)
Other information
Title: Knockdown of long noncoding RNA H19 sensitizes human glioma cells to temozolomide therapy.
Journal: Onco Targets Ther
Published: 2016
PubMed ID: 27366087