ncRNA basic information
ncRNA ID:
MIMAT0000232
ncRNA Database:
miRBase
ncRNA Name:
miR-199a-3p
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB01248 (APRD00932)
Drug Name:
Docetaxel
Drug Method:
The expression levels of miRNA were determined by RT-PCR and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs. MTT assay was used to test the drug-resistant phenotype changes in cancer cells via overregulation of miRNAs. A wound healing assay was performed to examine the capacity of cell migration.
Drug Response:
sensitive
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
cell line
Other information
Title:
MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2.
Journal:
J Cell Sci
Published:
2011
PubMed ID:
21807947