ncRNA basic information
ncRNA ID: ENSG00000253352
ncRNA Database: Ensembl
ncRNA Name: TUG1
ncRNA Type: lncRNA
ncRNA Expression: up-regulated
ncRNA Method: qRT-PCR
ncRNA Target Gene: Nrf2
ncRNA Pathway: NA
Evidence (ncRNA-drug): validated
drug basic information
Drug ID: DB00515 (APRD00359)
Drug Name: Cisplatin
Drug Method: The role of TUG1 in esophageal squamous cell carcinoma cells was detected using qRT-PCR, MTT assay, cell apoptosis assay, western blot analysis and RNA pull-down assay, etc.
Drug Response: resistant
Cancer basic information
Cancer: esophageal squamous cell carcinoma
Tissue/Cell: cell line ( TE-1,TE-1/DDP)
Other information
Title: LncRNA TUG1 promotes cisplatin resistance in esophageal squamous cell carcinoma cells by regulating Nrf2.
Journal: Acta Biochim Biophys Sin (Shanghai)
Published: 2019
PubMed ID: 31287493