ncRNA basic information
ncRNA ID:
ENST00000412153
ncRNA Database:
Ensembl
ncRNA Name:
NRAL
ncRNA Type:
lncRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
Nrf2
ncRNA Pathway:
NRAL/miR-340-5p/Nrf2
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The role of NRAL in hepatocellular carcinoma cells was detected using microarray assay, qRT-PCR, dual-luciferase reporter assay, RIP assay, CCK-8 assay, apoptosis assay and western blot analysis, etc.
Drug Response:
resistant
Cancer basic information
Cancer:
hepatocellular carcinoma
Tissue/Cell:
cell line (SMMC-7721,HepG2, HepG2/CDDP,SMMC-7721/CDDP,Huh7/CDDP)
Other information
Title:
NRAL mediates cisplatin resistance in hepatocellular carcinoma via miR-340-5p/Nrf2 axis.
Journal:
J Cell Commun Signal
Published:
2019
PubMed ID:
30030687