ncRNA basic information
ncRNA ID:
ENSG00000235770
ncRNA Database:
Ensembl
ncRNA Name:
LINC00607
ncRNA Type:
lncRNA
ncRNA Expression:
up-regulated
ncRNA Method:
Real-time RT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NF-kappaB p65/p53 signaling
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
The role of lncRNA 00607 in hepatocellular carcinoma cells was detected using western blot, Real-time RT-PCR analysis, proliferation assay, RNA FISH analysis, Xenograft tumor growth in nude mice, ChIP assay, etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
hepatocellular carcinoma
Tissue/Cell:
tissue and cell line (MHCC97H, HCCLM3, PLC, Hep3B, HepG2 and 7721 )
Other information
Title:
Long non-coding RNA 00607 as a tumor suppressor by modulating NF-kappaB p65/p53 signaling axis in hepatocellular carcinoma.
Journal:
Carcinogenesis
Published:
2018
PubMed ID:
30169594