ncRNA basic information
ncRNA ID:
ENSG00000177410
ncRNA Database:
Ensembl
ncRNA Name:
ZFAS1
ncRNA Type:
lncRNA
ncRNA Expression:
down-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
Wnt/Beta-catenin pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
In order to discover different expressions of lncRNA , we carried out the lncRNA sequencing of the ovarian cancer cell line A2780 and the paxitaxel resistant cell line A2817/PTX . The expression levels of lncRNA were determined by Real-time PCR . BLAST is used to select the sequence that were complementary or similarity to the differentially expressed lncRNA sequence using the human mRNA database . Then, RNAplex was used to calculate the complementary energy between two sequences . TFurthermore, we conducted the lncRNA-mRNA co-expression network to predict the potential multidrug resistant lncRNAs'targets.
Drug Response:
sensitive
Cancer basic information
Cancer:
stomach cancer
Tissue/Cell:
cell line (SGC7901)
Other information
Title:
Silencing of lncRNA ZFAS1 inhibits malignancies by blocking Wnt/Beta-catenin signaling in gastric cancer cells.
Journal:
Biosci Biotechnol Biochem
Published:
2018
PubMed ID:
29424266