ncRNA basic information
ncRNA ID:
ENSG00000251562
ncRNA Database:
Ensembl
ncRNA Name:
MALAT1
ncRNA Type:
lncRNA
ncRNA Expression:
down-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00853 (APRD00557)
Drug Name:
Temozolomide
Drug Method:
The role of MALAT1 in glioblastoma cells was detected using proliferation assay, wound-healing assay, antibody array, quantitative RT-PCR assay, flow cytometry assay, colony-formation assay and XTT assays, etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
glioblastoma
Tissue/Cell:
cell line (U87, T98G,LN-18,U87-luc2,U87R)
Other information
Title:
Targeted nanocomplex carrying siRNA against MALAT1 sensitizes glioblastoma to temozolomide.
Journal:
Nucleic Acids Res
Published:
2018
PubMed ID:
29202181