ncRNA basic information
ncRNA ID:
ENSG00000228630
ncRNA Database:
Ensembl
ncRNA Name:
HOTAIR
ncRNA Type:
lncRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-qPCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00441 (APRD00201)
Drug Name:
Gemcitabine
Drug Method:
The role of HOTAIR in pancreatic cancer stem-like cells was detected using RT-qPCR, transwell migration assay, serial replating experiments,CKK-8 assay and flow cytometric analysis,etc.
Drug Response:
resistant
Cancer basic information
Cancer:
pancreatic cancer
Tissue/Cell:
cell line (Panc-1)
Other information
Title:
Gemcitabine treatment causes resistance and malignancy of pancreatic cancer stem-like cells via induction of lncRNA HOTAIR.
Journal:
Exp Ther Med
Published:
2017
PubMed ID:
29201179