ncRNA basic information
ncRNA ID:
ENSG00000130600
ncRNA Database:
Ensembl
ncRNA Name:
H19
ncRNA Type:
lncRNA
ncRNA Expression:
up-regulated
ncRNA Method:
quantitative real-time RT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
cullin4A-MDR1 pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB11616
Drug Name:
Pirarubicin
Drug Method:
The role of H19 in breast cancer cells was detected using cell viability assay, microarray analysis, quantitative real-time RT-PCR, western blot analysis, etc.
Drug Response:
resistant
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
cell line (MCF-7,MCF-7/Dox400, MCF-7/Dox800, MCF-7/Dox1600,MCF-7/Con400, MCF-7/Con800 and MCF-7/Con1600)
Other information
Title:
LncRNA H19 is a major mediator of doxorubicin chemoresistance in breast cancer cells through a cullin4A-MDR1 pathway.
Journal:
Oncotarget
Published:
2017
PubMed ID:
29190892