ncRNA basic information
ncRNA ID:
ENSG00000268388
ncRNA Database:
Ensembl
ncRNA Name:
FENDRR
ncRNA Type:
lncRNA
ncRNA Expression:
down-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
ABCB1 and ABCC1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
The role of FENDRR in osteosarcoma cells was detected using drug-resistance assay, colony formation assay, qRT-PCR, cell cycle and apoptosis analysis, western blot analysis, bioinformatics analysis, in vivo tumor xenograft model, etc.
Drug Response:
resistant
Cancer basic information
Cancer:
osteosarcoma
Tissue/Cell:
cell line (MG63,SaoS2,HOS,MG63/DXR,KH-OS/DXR,U2-OS/DXR)
Other information
Title:
LncRNA FENDRR sensitizes doxorubicin-resistance of osteosarcoma cells through down-regulating ABCB1 and ABCC1.
Journal:
Oncotarget
Published:
2017
PubMed ID:
29069754