ncRNA basic information
ncRNA ID:
ENSG00000228630
ncRNA Database:
Ensembl
ncRNA Name:
HOTAIR
ncRNA Type:
lncRNA
ncRNA Expression:
down-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
Beclin-1, MDR, and P-gp
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The role of HOTAIR in endometrial cancer cells was detected using LncRNA profiling, CCK-8 assay, cell apoptosis assay and western blotting,etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
endometrial cancer
Tissue/Cell:
cell line
Other information
Title:
Autophagy regulated by lncRNA HOTAIR contributes to the cisplatin-induced resistance in endometrial cancer cells.
Journal:
Biotechnol Lett
Published:
2017
PubMed ID:
28721581