ncRNA basic information
ncRNA ID:
ENSG00000228630
ncRNA Database:
Ensembl
ncRNA Name:
HOTAIR
ncRNA Type:
lncRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
NA
Drug Name:
TRAIL therapy
Drug Method:
The role of HOTAIR in pancreatic cancer cells was detected using quantitative real-time PCR, western blot analysis, lentiviral constructs, analysis of apoptosis, chromatin immunoprecipitation (ChIP) assay,etc.
Drug Response:
resistant
Cancer basic information
Cancer:
pancreatic cancer
Tissue/Cell:
cell line (MiaPaCa-2, BxPC3, Suit2, and PANC-1 )
Other information
Title:
The long non-coding RNA HOTAIR enhances pancreatic cancer resistance to TNF-related apoptosis-inducing ligand.
Journal:
J Biol Chem
Published:
2017
PubMed ID:
28476883