ncRNA basic information
ncRNA ID:
ENSG00000260944
ncRNA Database:
Ensembl
ncRNA Name:
FOXC2-AS1
ncRNA Type:
lncRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
FOXC2
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
The role of FOXC2-AS1 in osteosarcoma cells was detected using CCK-8 assay, colony formation assay, qRT-PCR analyses, western blotting analysis, Xenograft transplantation and RNase protection assay,etc.
Drug Response:
resistant
Cancer basic information
Cancer:
osteosarcoma
Tissue/Cell:
cell line (MG63, SaoS2, HOS,KH-OS,KH-OS/DXR,U2-OS/DXR)
Other information
Title:
Antisense lncRNA FOXC2-AS1 promotes doxorubicin resistance in osteosarcoma by increasing the expression of FOXC2.
Journal:
Cancer Lett
Published:
2017
PubMed ID:
28323030