ncRNA basic information
ncRNA ID: MI0006379/MI0015974/MI0015975/MI0031511
ncRNA Database: miRBase
ncRNA Name: miR-1244
ncRNA Type: miRNA
ncRNA Expression: up-regulated
ncRNA Method: qRT-PCR
ncRNA Target Gene: MEF2D
ncRNA Pathway: NA
Evidence (ncRNA-drug): validated
drug basic information
Drug ID: DB00515 (APRD00359)
Drug Name: Cisplatin
Drug Method: The aim of this study was to investigate the function of miR-1244 in cisplatin-treated non-small cell lung cancer . The expression levels of miRNA were determined by Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and those of protein were by Western blot analysis. MTT assay was used to test the drug-resistant phenotype changes in cancer cells via overregulation of miRNAs.
Drug Response: sensitive
Cancer basic information
Cancer: lung non-small cell carcinoma
Tissue/Cell: cell line (A549, NCI-H522)
Other information
Title: Effect of miR-1244 on cisplatin-treated non-small cell lung cancer via MEF2D expression.
Journal: Oncol Rep
Published: 2017
PubMed ID: 28498474