ncRNA basic information
ncRNA ID:
ENSG00000249859
ncRNA Database:
Ensembl
ncRNA Name:
PVT1
ncRNA Type:
lncRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
apoptotic pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of lncRNA were determined by quantitative RT-PCR and those of protein were by Western blot analysis. Flow Cytometric Assay was used to determine if cells were viable, apoptotic, or necrotic. The CCK-8 assay was used to monitor the growth of the cells .
Drug Response:
resistant
Cancer basic information
Cancer:
ovarian cancer
Tissue/Cell:
cell line (SKOV-3/DDP,A2780/DDP,A2780)
Other information
Title:
Overexpression of long non-coding RNA PVT1 in ovarian cancer cells promotes cisplatin resistance by regulating apoptotic pathways.
Journal:
Int J Clin Exp Med
Published:
2015
PubMed ID:
26884974