ncRNA basic information
ncRNA ID:
NR_036444
ncRNA Database:
RefSeq
ncRNA Name:
FENDRR
ncRNA Type:
lncRNA
ncRNA Expression:
down-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
predicted
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
The expression levels of lncRNA were determined by quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR) . MTT assay was used to test the drug-resistant phenotype changes in cancer cells via overregulation of lncRNAs. lncRNA microarray was used to test the lncrna expression in different cell lines .GO analysis is a functional analysis associating differentially expressed mRNAs with GO categories. Pathway analysis for differentially expressed mRNAs was provided, based on the latest KEGG database
Drug Response:
resistant
Cancer basic information
Cancer:
osteosarcoma
Tissue/Cell:
cell line (MG63,MG63/DXR)
Other information
Title:
Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.
Journal:
Int J Clin Exp Pathol
Published:
2015
PubMed ID:
26464619