ncRNA basic information
ncRNA ID:
ENSG00000243197
ncRNA Database:
Ensembl
ncRNA Name:
LOC285194
ncRNA Type:
lncRNA
ncRNA Expression:
down-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The method of quantitative real-time polymerase chain reaction (qRT-PCR) was used to measure LOC285194 expression in pretreatment biopsy specimens and matched normal tissue derived from ESCC patients who underwent preoperative chemoradiotherapy followed by surgical resection or from those who received surgical resection alone. The association between LOC285194 expression and clinicopathological features and prognosis were then analyzed.
Drug Response:
resistant
Cancer basic information
Cancer:
esophageal squamous cell carcinoma
Tissue/Cell:
tissue and cell line (KYSE30, KYSE 70, KYSE 150, KYSE510, Eca109, Het-1A)
Other information
Title:
Association of decreased expression of long non-coding RNA LOC285194 with chemoradiotherapy resistance and poor prognosis in esophageal squamous cell carcinoma.
Journal:
J Transl Med
Published:
2014
PubMed ID:
25169763