ncRNA basic information
ncRNA ID:
ENSG00000130600
ncRNA Database:
Ensembl
ncRNA Name:
H19
ncRNA Type:
lncRNA
ncRNA Expression:
up-regulated
ncRNA Method:
Northern blot
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
The expression levels of lincRNA were determined by Northern-blot and those of protein were by Western blot analysis. MTT assay was used to test the drug-resistant phenotype changes in cancer cells via overregulation of lincRNAs.
Drug Response:
resistant
Cancer basic information
Cancer:
hepatocellular carcinoma
Tissue/Cell:
cell line (HepG2, R-HepG2)
Other information
Title:
Riboregulator H19 induction of MDR1-associated drug resistance in human hepatocellular carcinoma cells.
Journal:
Oncogene
Published:
2007
PubMed ID:
17297456