ncRNA basic information
ncRNA ID:
MI0003626
ncRNA Database:
miRBase
ncRNA Name:
miR-613
ncRNA Type:
miRNA
ncRNA Expression:
down-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
SOX9
ncRNA Pathway:
SOX9 pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined by Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs. MTT assay was used to test the drug-resistant phenotype changes in cancer cells via overregulation of miRNAs.
Drug Response:
resistant
Cancer basic information
Cancer:
liver cancer
Tissue/Cell:
tissue and cell line ( Huh7 and HCCLM3 )
Other information
Title:
miR-613 inhibits liver cancer stem cell expansion by regulating SOX9 pathway.
Journal:
Gene
Published:
2019
PubMed ID:
31075412