ncRNA basic information
ncRNA ID:
MI0003626
ncRNA Database:
miRBase
ncRNA Name:
miR-613
ncRNA Type:
miRNA
ncRNA Expression:
down-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
SOX9
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression of miR-613 and Sex-determining region Y (SRY)-box 9 (SOX9) in GC tissues and cell lines was detected by using qRT-PCR. Cell migration and viability were measured by the wound healing assay and CCK-8 assays. Western blot and dual-luciferase reporter were done to identify the target gene of miR-613.
Drug Response:
resistant
Cancer basic information
Cancer:
stomach cancer
Tissue/Cell:
tissue and cell line ( MGC-803, HGC-27, HGC-27,SGC-7901,GES-1 )
Other information
Title:
MicroRNA-613 induces the sensitivity of gastric cancer cells to cisplatin through targeting SOX9 expression.
Journal:
Am J Transl Res
Published:
2019
PubMed ID:
30899388